To estimate the prevalence of New
Onset Diabetes after Liver Transplantation (NODAT) and to investigate the
possible risk factors. Methods: This retrospective study comprises 213 patients
subjected to living donor liver transplantation (LDLT). Patients’ data were
collected from medical registry files for a period of two years after
transplant. Results: Of the total 213 recipients, complete data for the whole
study period were available for 164 recipients who were enrolled in this study.
Fifty one 51 (31.1%) patients were already diabetic prior to transplantation.
The prevalence of NODAT was 27.43% (31/113). Eight of NODAT cases (25.8%) were
transient with recovery within 6-months period in 5/8 cases while the other 3
cases recovered in more than 6 months to a year. The only drug that showed statistically significant difference was tacrolimus (p=0.02). Interestingly,
three pre-transplant diabetics (3/51, 5.9%) recovered after liver transplant
with elimination of their anti-diabetic therapy. Conclusion: NODAT is a common
medical complication that occurs in 27.4% of liver transplant recipients.
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