Nano sphere systems have great
potentials, being able to convert poorly soluble, poorly absorbed and labile
biologically active substance into promising deliverable drugs. The core of this system can enclose a variety of drugs, enzymes, genes and is characterized
by a long circulation time due to the hydrophilic shell which prevents
recognition by the reticular-endothelial system. To optimize this drug delivery
system, greater understanding of the different mechanisms of biological
interactions, and particle engineering, is still required. Further advances are
needed in order to turn the concept of nanoparticles technology into a
realistic practical application as the next generation of drug delivery system.
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